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Pannexin 1 inhibits rhabdomyosarcoma progression through a mechanism independent of its canonical channel function

Rhabdomyosarcoma (RMS) is an aggressive soft tissue sarcoma of childhood thought to arise from impaired differentiation of skeletal muscle progenitors. We have recently identified Pannexin 1 (PANX1) channels as a novel regulator of skeletal myogenesis. In the present study, we determined that PANX1...

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Detalles Bibliográficos
Autores principales: Xiang, Xiao, Langlois, Stéphanie, St-Pierre, Marie-Eve, Barré, Jessica F., Grynspan, David, Purgina, Bibianna, Cowan, Kyle N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6246549/
https://www.ncbi.nlm.nih.gov/pubmed/30459312
http://dx.doi.org/10.1038/s41389-018-0100-4