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Pannexin 1 inhibits rhabdomyosarcoma progression through a mechanism independent of its canonical channel function
Rhabdomyosarcoma (RMS) is an aggressive soft tissue sarcoma of childhood thought to arise from impaired differentiation of skeletal muscle progenitors. We have recently identified Pannexin 1 (PANX1) channels as a novel regulator of skeletal myogenesis. In the present study, we determined that PANX1...
Autores principales: | Xiang, Xiao, Langlois, Stéphanie, St-Pierre, Marie-Eve, Barré, Jessica F., Grynspan, David, Purgina, Bibianna, Cowan, Kyle N. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6246549/ https://www.ncbi.nlm.nih.gov/pubmed/30459312 http://dx.doi.org/10.1038/s41389-018-0100-4 |
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