Polymorphisms in mTOR and Calcineurin Signaling Pathways Are Associated With Long-Term Clinical Outcomes in Kidney Transplant Recipients

Monitoring of immunosuppressive drugs, such as calcineurin and mTOR inhibitors, is essential to avoid undesirable kidney transplant outcomes. Polymorphisms in pharmacokinetics-related genes have been associated with variability in blood levels of immunosuppressive drugs and adverse effects, but infl...

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Detalles Bibliográficos
Autores principales: Campos-Salazar, Antony Brayan, Genvigir, Fabiana Dalla Vecchia, Felipe, Claudia Rosso, Tedesco-Silva, Helio, Medina-Pestana, José, Monteiro, Gabriela Vieira, Basso, Rodrigo de Gouveia, Cerda, Alvaro, Hirata, Mario Hiroyuki, Hirata, Rosario Dominguez Crespo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6246626/
https://www.ncbi.nlm.nih.gov/pubmed/30487748
http://dx.doi.org/10.3389/fphar.2018.01296

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6246626/
https://www.ncbi.nlm.nih.gov/pubmed/30487748
http://dx.doi.org/10.3389/fphar.2018.01296

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