BRAF V600E Inhibitor (Vemurafenib) for BRAF V600E Mutated Low Grade Gliomas

Low-grade gliomas (LGG) are the most common central nervous system tumors in children. Prognosis depends on complete surgical resection. For patients not amenable of gross total resection (GTR) new approaches are needed. The BRAF mutation V600E is critical for the pathogenesis of pediatric gliomas a...

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Detalles Bibliográficos
Autores principales: Del Bufalo, Francesca, Ceglie, Giulia, Cacchione, Antonella, Alessi, Iside, Colafati, Giovanna Stefania, Carai, Andrea, Diomedi-Camassei, Francesca, De Billy, Emmanuel, Agolini, Emanuele, Mastronuzzi, Angela, Locatelli, Franco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6246660/
https://www.ncbi.nlm.nih.gov/pubmed/30488019
http://dx.doi.org/10.3389/fonc.2018.00526

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6246660/
https://www.ncbi.nlm.nih.gov/pubmed/30488019
http://dx.doi.org/10.3389/fonc.2018.00526

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