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Silencing of Hypoglossal Motoneurons Leads to Sleep Disordered Breathing in Lean Mice

Obstructive Sleep Apnea (OSA) is a prevalent condition and a major cause of morbidity and mortality in Western Society. The loss of motor input to the tongue and specifically to the genioglossus muscle during sleep is associated with pharyngeal collapsibility and the development of OSA. We applied a...

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Detalles Bibliográficos
Autores principales: Fleury Curado, Thomaz A., Pho, Huy, Dergacheva, Olga, Berger, Slava, Lee, Rachel, Freire, Carla, Asherov, Aya, Sennes, Luis U., Mendelowitz, David, Schwartz, Alan R., Polotsky, Vsevolod Y.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6246694/
https://www.ncbi.nlm.nih.gov/pubmed/30487776
http://dx.doi.org/10.3389/fneur.2018.00962