Rapamycin attenuates mitochondrial injury and renal tubular cell apoptosis in experimental contrast-induced acute kidney injury in rats

Reactive oxygen species (ROS) overproduction and renal tubular epithelial cell (TEC) apoptosis are key mechanisms of contrast-induced acute kidney injury (CI-AKI). Mitochondria are the main source of intracellular ROS. In the present study, the characteristics of mitophagy and the effects of rapamyc...

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Detalles Bibliográficos
Autores principales: Yang, Xueyan, Yan, Xiaojie, Yang, Dingping, Zhou, Junke, Song, Jie, Yang, Dingwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2018
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6246763/
https://www.ncbi.nlm.nih.gov/pubmed/30341250
http://dx.doi.org/10.1042/BSR20180876

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6246763/
https://www.ncbi.nlm.nih.gov/pubmed/30341250
http://dx.doi.org/10.1042/BSR20180876

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