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Systematic identification of Celastrol-binding proteins reveals that Shoc2 is inhibited by Celastrol

Colorectal cancer (CRC) is the third most commonly diagnosed cancer. Celastrol exhibits anti-tumor activities in a variety of cancers. However, the effect of Celastrol on human CRC and the underlying mechanisms still need to be elucidated. The present study aimed to use in vitro and in vivo methods...

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Detalles Bibliográficos
Autores principales: Xiao-pei, Huang, Ji-kuai, Chen, Xue, Wei, Dong, Yi-Fan, Yan, Lang, Xiao-fang, Zhang, Ya-min, Pan, Wen-jun, Chang, Jiang-bo, Zhu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6246769/
https://www.ncbi.nlm.nih.gov/pubmed/30333251
http://dx.doi.org/10.1042/BSR20181233