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Effect of Age on NK Cell Compartment in Chronic Myeloid Leukemia Patients Treated With Tyrosine Kinase Inhibitors

Natural killer (NK) cells are a very important component of the innate immune response involved in the lysis of virus infected and tumor cells. Aging has a profound impact in the frequency, phenotype and function of NK cells. Chronic Myeloid Leukemia (CML) is caused by the BCR-ABL gene formation enc...

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Detalles Bibliográficos
Autores principales: Rodrigues-Santos, Paulo, López-Sejas, Nelson, Almeida, Jani Sofia, Ruzičková, Lenka, Couceiro, Patricia, Alves, Vera, Campos, Carmen, Alonso, Corona, Tarazona, Raquel, Freitas-Tavares, Paulo, Solana, Rafael, Santos-Rosa, Manuel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6246921/
https://www.ncbi.nlm.nih.gov/pubmed/30487792
http://dx.doi.org/10.3389/fimmu.2018.02587