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Effect of Age on NK Cell Compartment in Chronic Myeloid Leukemia Patients Treated With Tyrosine Kinase Inhibitors
Natural killer (NK) cells are a very important component of the innate immune response involved in the lysis of virus infected and tumor cells. Aging has a profound impact in the frequency, phenotype and function of NK cells. Chronic Myeloid Leukemia (CML) is caused by the BCR-ABL gene formation enc...
Autores principales: | Rodrigues-Santos, Paulo, López-Sejas, Nelson, Almeida, Jani Sofia, Ruzičková, Lenka, Couceiro, Patricia, Alves, Vera, Campos, Carmen, Alonso, Corona, Tarazona, Raquel, Freitas-Tavares, Paulo, Solana, Rafael, Santos-Rosa, Manuel |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6246921/ https://www.ncbi.nlm.nih.gov/pubmed/30487792 http://dx.doi.org/10.3389/fimmu.2018.02587 |
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