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An Aurora kinase inhibitor, AMG900, inhibits glioblastoma cell proliferation by disrupting mitotic progression

The Aurora kinase family of serine/threonine protein kinases comprises Aurora A, B, and C and plays an important role in mitotic progression. Several inhibitors of Aurora kinase have been developed as anti‐cancer therapeutics. Here, we examined the effects of a pan‐Aurora kinase inhibitor, AMG900, a...

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Detalles Bibliográficos
Autores principales: Ryu, Jaewook, Pyo, Jaehyuk, Lee, Chang‐Woo, Kim, Ja‐Eun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6246935/
https://www.ncbi.nlm.nih.gov/pubmed/30221846
http://dx.doi.org/10.1002/cam4.1771