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Strong impact of sulfotransferases on DNA adduct formation by 4‐aminobiphenyl in bladder and liver in mice

Bladder cancer risk is 3‐4 times higher in men than women, but the reason is poorly understood. In mice, male bladder is also more susceptible than female bladder to 4‐aminobiphenyl (ABP), a major human bladder carcinogen; however, female liver is more susceptible than male liver to ABP. We investig...

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Detalles Bibliográficos
Autores principales: Li, Yun, Chen, Zhidan, Paonessa, Joseph D., Meinl, Walter, Bhattacharya, Arup, Glatt, Hansruedi, Vouros, Paul, Zhang, Yuesheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6246946/
https://www.ncbi.nlm.nih.gov/pubmed/30306738
http://dx.doi.org/10.1002/cam4.1779