Fc‐gamma receptor polymorphisms, cetuximab therapy, and overall survival in the CCTG CO.20 trial of metastatic colorectal cancer

BACKGROUND: Two germ line Fc‐γ receptor (FCGR) polymorphisms, rs1801274 [FCGR2A; His(H)131Arg(R)] and rs396991 [FCGR3A; Phe(F)158Val(V)], produce altered proteins through amino acid substitutions. We previously reported that the FCGR2A H/H genotype was associated with longer overall survival (OS) in...

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Detalles Bibliográficos
Autores principales: Shepshelovich, Daniel, Townsend, Amanda R., Espin‐Garcia, Osvaldo, Latifovic, Lidija, O’Callaghan, Chris J., Jonker, Derek J., Tu, Dongsheng, Chen, Eric, Morgen, Eric, Price, Timothy J., Shapiro, Jeremy, Siu, Lillian L., Kubo, Michiaki, Dobrovic, Alexander, Ratain, Mark J., Xu, Wei, Mushiroda, Taisei, Liu, Geoffrey
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Clinical Cancer Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6246957/
https://www.ncbi.nlm.nih.gov/pubmed/30318772
http://dx.doi.org/10.1002/cam4.1819

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6246957/
https://www.ncbi.nlm.nih.gov/pubmed/30318772
http://dx.doi.org/10.1002/cam4.1819

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