The Mechanism behind Bacterial Lipoprotein Release: Phenol-Soluble Modulins Mediate Toll-Like Receptor 2 Activation via Extracellular Vesicle Release from Staphylococcus aureus

The innate immune system uses Toll-like receptor (TLR) 2 to detect conserved bacterial lipoproteins of invading pathogens. The lipid anchor attaches lipoproteins to the cytoplasmic membrane and prevents their release from the bacterial cell envelope. How bacteria release lipoproteins and how these m...

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Detalles Bibliográficos
Autores principales: Schlatterer, Katja, Beck, Christian, Hanzelmann, Dennis, Lebtig, Marco, Fehrenbacher, Birgit, Schaller, Martin, Ebner, Patrick, Nega, Mulugeta, Otto, Michael, Kretschmer, Dorothee, Peschel, Andreas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6247081/
https://www.ncbi.nlm.nih.gov/pubmed/30459192
http://dx.doi.org/10.1128/mBio.01851-18

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6247081/
https://www.ncbi.nlm.nih.gov/pubmed/30459192
http://dx.doi.org/10.1128/mBio.01851-18

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