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Cryptococcus neoformans Cda1 and Its Chitin Deacetylase Activity Are Required for Fungal Pathogenesis

Chitin is an essential component of the cell wall of Cryptococcus neoformans conferring structural rigidity and integrity under diverse environmental conditions. Chitin deacetylase genes encode the enyzmes (chitin deacetylases [Cdas]) that deacetylate chitin, converting it to chitosan. The functiona...

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Detalles Bibliográficos
Autores principales: Upadhya, Rajendra, Baker, Lorina G., Lam, Woei C., Specht, Charles A., Donlin, Maureen J., Lodge, Jennifer K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6247093/
https://www.ncbi.nlm.nih.gov/pubmed/30459196
http://dx.doi.org/10.1128/mBio.02087-18