ATP promotes immunosuppressive capacities of mesenchymal stromal cells by enhancing the expression of indoleamine dioxygenase

INTRODUCTION: MSCs are often found within tumors, promote cancer progression and enhance metastasis. MSCs can act as immuosuppressive cells, partially due to the expression of the enzyme indoleamine dioxygenase (IDO) which converts tryptophan to kynurenine. Decreased concentration of tryptophan and...

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Detalles Bibliográficos
Autores principales: Lotfi, Ramin, Steppe, Lena, Hang, Regina, Rojewski, Markus, Massold, Marina, Jahrsdörfer, Bernd, Schrezenmeier, Hubert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6247240/
https://www.ncbi.nlm.nih.gov/pubmed/30306723
http://dx.doi.org/10.1002/iid3.236

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6247240/
https://www.ncbi.nlm.nih.gov/pubmed/30306723
http://dx.doi.org/10.1002/iid3.236

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