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Sodium Dichloroacetate Pharmacological Effect as Related to Na–K–2Cl Cotransporter Inhibition in Rats

The study objective was to investigate a possible sodium dichloroacetate (DCA) pharmacological mechanism causing an increase in diuresis in rats. The aim was to define characteristics of 24-hour urinary Na(+), K(+), Cl(−), Ca(2+), and Mg(2+) excretion in Wistar male rats and to evaluate effect of a...

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Detalles Bibliográficos
Autores principales: Stanevičiūtė, Jūratė, Juknevičienė, Milda, Palubinskienė, Jolita, Balnytė, Ingrida, Valančiūtė, Angelija, Vosyliūtė, Rūta, Sužiedėlis, Kęstutis, Lesauskaitė, Vaiva, Stakišaitis, Donatas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6247491/
https://www.ncbi.nlm.nih.gov/pubmed/30479587
http://dx.doi.org/10.1177/1559325818811522