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Molecular mechanism of phosphoinositides' specificity for the inwardly rectifying potassium channel Kir2.2
Phosphoinositides are essential signaling lipids that play a critical role in regulating ion channels, and their dysregulation often results in fatal diseases including cardiac arrhythmia and paralysis. Despite decades of intensive research, the underlying molecular mechanism of lipid agonism and sp...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Royal Society of Chemistry
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6247517/ https://www.ncbi.nlm.nih.gov/pubmed/30542582 http://dx.doi.org/10.1039/c8sc01284a |