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Cancer-Associated Fibroblasts in Pancreatic Cancer: Should They Be Deleted or Reeducated?
Pancreatic ductal adenocarcinoma is characterized by an extensive stromal response called desmoplasia. Within the tumor stroma, cancer-associated fibroblasts (CAFs) are the primary cell type. CAFs have been shown to play a role in pancreatic cancer progression; they secrete growth factors, inflammat...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
SAGE Publications
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6247553/ https://www.ncbi.nlm.nih.gov/pubmed/30136592 http://dx.doi.org/10.1177/1534735418794884 |