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Purinergic 2X7 Receptor is Involved in the Podocyte Damage of Obesity-Related Glomerulopathy via Activating Nucleotide-Binding and Oligomerization Domain-Like Receptor Protein 3 Inflammasome

BACKGROUND: The nucleotide-binding and oligomerization domain-like receptor protein 3 (NLRP3) inflammasome composed of NLRP3, apoptosis-associated speck-like protein containing CARD (ASC), and caspase-1 is engaged in the inflammatory response of many kidney diseases and can be activated by purinergi...

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Detalles Bibliográficos
Autores principales: Hou, Xiao-Xia, Dong, Hong-Rui, Sun, Li-Jun, Yang, Min, Cheng, Hong, Chen, Yi-Pu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6247604/
https://www.ncbi.nlm.nih.gov/pubmed/30425198
http://dx.doi.org/10.4103/0366-6999.245270