STING-mediated type-I interferons contribute to the neuroinflammatory process and detrimental effects following traumatic brain injury

BACKGROUND: Traumatic brain injury (TBI) represents a major cause of disability and death worldwide with sustained neuroinflammation and autophagy dysfunction contributing to the cellular damage. Stimulator of interferon genes (STING)-induced type-I interferon (IFN) signalling is known to be essenti...

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Detalles Bibliográficos
Autores principales: Abdullah, Amar, Zhang, Moses, Frugier, Tony, Bedoui, Sammy, Taylor, Juliet M., Crack, Peter J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6247615/
https://www.ncbi.nlm.nih.gov/pubmed/30463579
http://dx.doi.org/10.1186/s12974-018-1354-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6247615/
https://www.ncbi.nlm.nih.gov/pubmed/30463579
http://dx.doi.org/10.1186/s12974-018-1354-7

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