Cargando…

STING-mediated type-I interferons contribute to the neuroinflammatory process and detrimental effects following traumatic brain injury

BACKGROUND: Traumatic brain injury (TBI) represents a major cause of disability and death worldwide with sustained neuroinflammation and autophagy dysfunction contributing to the cellular damage. Stimulator of interferon genes (STING)-induced type-I interferon (IFN) signalling is known to be essenti...

Descripción completa

Detalles Bibliográficos
Autores principales:	Abdullah, Amar, Zhang, Moses, Frugier, Tony, Bedoui, Sammy, Taylor, Juliet M., Crack, Peter J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2018
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6247615/ https://www.ncbi.nlm.nih.gov/pubmed/30463579 http://dx.doi.org/10.1186/s12974-018-1354-7

Ejemplares similares

The Complexity of the cGAS-STING Pathway in CNS Pathologies
por: Fryer, Amelia L., et al.
Publicado: (2021)

STING-Mediated Autophagy Is Protective against H(2)O(2)-Induced Cell Death
por: Abdullah, Amar, et al.
Publicado: (2020)

Type-1 interferons contribute to oxygen glucose deprivation induced neuro-inflammation in BE(2)M17 human neuroblastoma cells
por: Minter, Myles Robert, et al.
Publicado: (2014)

Amyloid-β drives a type-1 interferon mediated neuro-inflammatory response in Alzheimer’s disease
por: Minter, Myles, et al.
Publicado: (2013)

Abrogation of type-I interferon signalling alters the microglial response to Aβ(1–42)
por: Moore, Zachery, et al.
Publicado: (2020)

Both STING and MAVS Fish Orthologs Contribute to the Induction of Interferon Mediated by RIG-I
por: Biacchesi, Stéphane, et al.
Publicado: (2012)

Soluble amyloid triggers a myeloid differentiation factor 88 and interferon regulatory factor 7 dependent neuronal type-1 interferon response in vitro
por: Minter, Myles Robert, et al.
Publicado: (2015)

The role of STING signaling in central nervous system infection and neuroinflammatory disease
por: Fritsch, Lauren E., et al.
Publicado: (2023)

TYPE I INTERFERON-MEDIATED NEUROINFLAMMATORY PROGRAM AND SYNAPSE LOSS IN ALZHEIMER’S DISEASE
por: Roy, Ethan, et al.
Publicado: (2019)

cGAS-STING-mediated IFNI Response in Host Defense and Neuroinflammatory Diseases
por: Chen, Kai, et al.
Publicado: (2022)

Ablation of Type-1 IFN Signaling in Hematopoietic Cells Confers Protection Following Traumatic Brain Injury123
por: Karve, Ila P., et al.
Publicado: (2016)

Neuroinflammatory responses to traumatic brain injury
por: Paiva, Wellingson Silva, et al.
Publicado: (2015)

Neuroinflammatory mechanisms of post-traumatic epilepsy
por: Mukherjee, Sanjib, et al.
Publicado: (2020)

Interferon- and STING-independent induction of type I interferon stimulated genes during fractionated irradiation
por: Goedegebuure, Ruben S. A., et al.
Publicado: (2021)

Human STING Is Regulated by an Autoinhibitory Mechanism for Type I Interferon Production
por: Qi, Shishi, et al.
Publicado: (2022)

Type I Interferon Induction Is Detrimental during Infection with the Whipple's Disease Bacterium, Tropheryma whipplei
por: Al Moussawi, Khatoun, et al.
Publicado: (2010)

Dampened STING-Dependent Interferon Activation in Bats
por: Xie, Jiazheng, et al.
Publicado: (2018)

Deletion of the type-1 interferon receptor in APP(SWE)/PS1(ΔE9) mice preserves cognitive function and alters glial phenotype
por: Minter, Myles R., et al.
Publicado: (2016)

Type I Interferon Response Is Mediated by NLRX1-cGAS-STING Signaling in Brain Injury
por: Fritsch, Lauren E., et al.
Publicado: (2022)

Modelling neuroinflammatory phenotypes in vivo
por: Buckwalter, Marion S, et al.
Publicado: (2004)

Crosstalk Between Autophagy and the cGAS–STING Signaling Pathway in Type I Interferon Production
por: Zhang, Kunli, et al.
Publicado: (2021)

Endothelial type I interferon response and brain diseases: identifying STING as a therapeutic target
por: Duarte, Nádia, et al.
Publicado: (2023)

ARF1 prevents aberrant type I interferon induction by regulating STING activation and recycling
por: Hirschenberger, Maximilian, et al.
Publicado: (2023)

High-throughput screening for small molecule inhibitors of the type-I interferon signaling pathway
por: Yuliantie, Elita, et al.
Publicado: (2018)

Corrigendum: Type I Interferon Response Is Mediated by NLRX1-cGAS-STING Signaling in Brain Injury
por: Fritsch, Lauren E., et al.
Publicado: (2022)

Stimulator of Interferon Genes (STING) Triggers Adipocyte Autophagy
por: Varga, Kornél Z., et al.
Publicado: (2023)

Targeting the stimulator of interferon genes (STING) in breast cancer
por: Ying-Rui, Ma, et al.
Publicado: (2023)

Interferon Gamma: Influence on Neural Stem Cell Function in Neurodegenerative and Neuroinflammatory Disease
por: Kulkarni, Apurva, et al.
Publicado: (2016)

Editorial: Exploring neuroinflammatory pathways that contribute to chronic pain
por: Lione, Lisa A., et al.
Publicado: (2022)

Interdependent and independent roles of type I interferons and IL-6 in innate immune, neuroinflammatory and sickness behaviour responses to systemic poly I:C
por: Murray, Carol, et al.
Publicado: (2015)

Cutibacterium acnes Infection Induces Type I Interferon Synthesis Through the cGAS-STING Pathway
por: Fischer, Katrin, et al.
Publicado: (2020)

Beneficial bacteria activate type-I interferon production via the intracellular cytosolic sensors STING and MAVS
por: Gutierrez-Merino, Jorge, et al.
Publicado: (2020)

The role of bioactive lipids in attenuating the neuroinflammatory cascade in traumatic brain injury
por: Poblete, Roy A., et al.
Publicado: (2020)

Characterization of neuroinflammatory positron emission tomography biomarkers in chronic traumatic encephalopathy
por: Varlow, Cassis, et al.
Publicado: (2022)

Interferon-β Intensifies Interleukin-23-Driven Pathogenicity of T Helper Cells in Neuroinflammatory Disease
por: Agasing, Agnieshka, et al.
Publicado: (2021)

Reactive oxygen species oxidize STING and suppress interferon production
por: Tao, Lili, et al.
Publicado: (2020)

Identification and function analysis of canine stimulator of interferon gene (STING)
por: Zhang, Yuxiang, et al.
Publicado: (2017)

Activation of Stimulation of Interferon Genes (STING) Signal and Cancer Immunotherapy
por: Luo, Kewang, et al.
Publicado: (2022)

The role of dendritic cells in immunity against primary herpes simplex virus infections
por: Bedoui, Sammy, et al.
Publicado: (2014)

Potentially Detrimental Effects of Hyperosmolality in Patients Treated for Traumatic Brain Injury
por: Dabrowski, Wojciech, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_ppdfurm9g4us9cvtbm9ue9dsjp