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CYP genetic variants and toxicity related to anti-tubercular agents: a systematic review and meta-analysis

BACKGROUND: Treatment with anti-tuberculosis drugs may cause patients to experience serious adverse effects. Genetic factors, such as polymorphisms of CYP genes, may increase the likelihood of a patient experiencing such adverse drug reactions. In this systematic review and meta-analysis, we synthes...

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Detalles Bibliográficos
Autores principales: Richardson, Marty, Kirkham, Jamie, Dwan, Kerry, Sloan, Derek J., Davies, Geraint, Jorgensen, Andrea L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6247669/
https://www.ncbi.nlm.nih.gov/pubmed/30458875
http://dx.doi.org/10.1186/s13643-018-0861-z