Lipid nanoparticles that deliver IL-12 messenger RNA suppress tumorigenesis in MYC oncogene-driven hepatocellular carcinoma

Interleukin-12 (IL-12) is a promising candidate for cancer immunotherapy because of its ability to activate a number of host immune subsets that recognize and destroy cancer cells. We found that human hepatocellular carcinoma (HCC) patients with higher than median levels of IL-12 have significantly...

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Detalles Bibliográficos
Autores principales: Lai, Ian, Swaminathan, Srividya, Baylot, Virginie, Mosley, Adriane, Dhanasekaran, Renumathy, Gabay, Meital, Felsher, Dean W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6247677/
https://www.ncbi.nlm.nih.gov/pubmed/30458889
http://dx.doi.org/10.1186/s40425-018-0431-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6247677/
https://www.ncbi.nlm.nih.gov/pubmed/30458889
http://dx.doi.org/10.1186/s40425-018-0431-x

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