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Glial-neuronal signaling mechanisms underlying the neuroinflammatory effects of manganese

BACKGROUND: Exposure to increased manganese (Mn) causes inflammation and neuronal injury in the cortex and basal ganglia, resulting in neurological symptoms resembling Parkinson’s disease. The mechanisms underlying neuronal death from exposure to Mn are not well understood but involve inflammatory a...

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Detalles Bibliográficos
Autores principales: Popichak, Katriana A., Afzali, Maryam F., Kirkley, Kelly S., Tjalkens, Ronald B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6247759/
https://www.ncbi.nlm.nih.gov/pubmed/30463564
http://dx.doi.org/10.1186/s12974-018-1349-4