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Divergent Effects of Cyclophilin-D Inhibition on the Female Rat Heart: Acute Versus Chronic Post-Myocardial Infarction

BACKGROUND/AIMS: The mitochondrial permeability transition pore opening plays a critical role in the pathogenesis of myocardial infarction. Inhibition of cyclophilin-D (CyP-D), a key regulator of the mitochondrial permeability transition pore, has been shown to exert cardioprotective effects against...

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Detalles Bibliográficos
Autores principales: Parodi-Rullán, Rebecca M., Soto-Prado, Jadira, Vega-Lugo, Jesús, Chapa-Dubocq, Xavier, Díaz-Cordero, Sara I., Javadov, Sabzali
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6247791/
https://www.ncbi.nlm.nih.gov/pubmed/30282073
http://dx.doi.org/10.1159/000494006