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Meffil: efficient normalization and analysis of very large DNA methylation datasets
MOTIVATION: DNA methylation datasets are growing ever larger both in sample size and genome coverage. Novel computational solutions are required to efficiently handle these data. RESULTS: We have developed meffil, an R package designed for efficient quality control, normalization and epigenome-wide...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6247925/ https://www.ncbi.nlm.nih.gov/pubmed/29931280 http://dx.doi.org/10.1093/bioinformatics/bty476 |