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Meffil: efficient normalization and analysis of very large DNA methylation datasets

MOTIVATION: DNA methylation datasets are growing ever larger both in sample size and genome coverage. Novel computational solutions are required to efficiently handle these data. RESULTS: We have developed meffil, an R package designed for efficient quality control, normalization and epigenome-wide...

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Detalles Bibliográficos
Autores principales: Min, J L, Hemani, G, Davey Smith, G, Relton, C, Suderman, M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6247925/
https://www.ncbi.nlm.nih.gov/pubmed/29931280
http://dx.doi.org/10.1093/bioinformatics/bty476