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A New Concept of the Old Inhibitor NSC 74859 in Alleviating Cardiac Allograft Rejection and Extending Allograft Survival in Mice

BACKGROUND: STAT1/4 has been suggested to be involved in cardiac allograft rejection. However, no direct evidence regarding STAT3 has been established in cardiac allograft rejection. Here, we hypothesized that inhibition of STAT3 attenuates cardiac allograft rejection. MATERIAL/METHODS: To test our...

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Detalles Bibliográficos
Autores principales: Lai, Yiquan, Kuang, Feng, Shan, Zhonggui, Liu, Huaqing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Scientific Literature, Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6248023/
https://www.ncbi.nlm.nih.gov/pubmed/29097651
http://dx.doi.org/10.12659/AOT.905688