Antifibrotic Effects of Hepatocyte Growth Factor on Endothelial-to-Mesenchymal Transition via Transforming Growth Factor-Beta1 (TGF-β1)/Smad and Akt/mTOR/P70S6K Signaling Pathways

BACKGROUND: The related mechanisms involved in allograft interstitial fibrosis and chronic allograft dysfunction (CAD), following renal transplant, remain largely unknown. Here, we explored the role of hepatocyte growth factor (HGF) treatment on the endothelial-to-mesenchymal transition (EndMT) as a...

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Detalles Bibliográficos
Autores principales: Wang, Zijie, Fei, Shuang, Suo, Chuanjian, Han, Zhijian, Tao, Jun, Xu, Zhen, Zhao, Chunchun, Tan, Ruoyun, Gu, Min
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Scientific Literature, Inc. 2018
Materias:
Original Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6248046/
https://www.ncbi.nlm.nih.gov/pubmed/29292365
http://dx.doi.org/10.12659/AOT.906700

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6248046/
https://www.ncbi.nlm.nih.gov/pubmed/29292365
http://dx.doi.org/10.12659/AOT.906700

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