Inhibition of ROS-mediated activation Src-MAPK/AKT signaling by orientin alleviates H(2)O(2)-induced apoptosis in PC12 cells

PURPOSE: Reactive oxygen species (ROS) are considered a direct cause of neurodegenerative diseases (NDDs). Drugs developed to target ROS are effective for the treatment of NDDs. Orientin is a pyrone glucoside extracted from Polygonum orientale, and it exhibits many pharmacological activities. In thi...

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Detalles Bibliográficos
Autores principales: Qi, Shimei, Feng, Zunyong, Li, Qiang, Qi, Zhilin, Zhang, Yao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2018
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6248275/
https://www.ncbi.nlm.nih.gov/pubmed/30510405
http://dx.doi.org/10.2147/DDDT.S178217

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6248275/
https://www.ncbi.nlm.nih.gov/pubmed/30510405
http://dx.doi.org/10.2147/DDDT.S178217

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