Cargando…

Negative Correlation Between Hepatitis C Virus (HCV) and Let-7 MicroRNA Family in Transplanted Livers: The Role of rs868 Single-Nucleotide Polymorphism

BACKGROUND: Genetic alterations of TGF-β pathway members, including its transmembrane receptor, TGFBR1, may influence the course of HCV infection. Rs868 is a single-nucleotide polymorphism of the 3′UTR region of TGFBR1, located in a binding site for the conserved let-7/miR98 microRNA family. Previou...

Descripción completa

Detalles Bibliográficos
Autores principales: Sajjad, Emir Ahmed, Radkowski, Marek, Perkowska-Ptasińska, Agnieszka, Pacholczyk, Marek, Durlik, Magdalena, Fedorowicz, Mikołaj, Pietrzak, Renata, Ziarkiewicz-Wróblewska, Bogna, Włodarski, Paweł, Malejczyk, Jacek
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Scientific Literature, Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6248281/
https://www.ncbi.nlm.nih.gov/pubmed/29061957
http://dx.doi.org/10.12659/AOT.905540