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A novel mode of capping protein-regulation by twinfilin

Cellular actin assembly is controlled at the barbed ends of actin filaments, where capping protein (CP) limits polymerization. Twinfilin is a conserved in vivo binding partner of CP, yet the significance of this interaction has remained a mystery. Here, we discover that the C-terminal tail of Twinfi...

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Detalles Bibliográficos
Autores principales: Johnston, Adam B, Hilton, Denise M, McConnell, Patrick, Johnson, Britney, Harris, Meghan T, Simone, Avital, Amarasinghe, Gaya K, Cooper, John A, Goode, Bruce L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6249002/
https://www.ncbi.nlm.nih.gov/pubmed/30351272
http://dx.doi.org/10.7554/eLife.41313