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Conserved motifs in the hypervariable domain of chikungunya virus nsP3 required for transmission by Aedes aegypti mosquitoes

BACKGROUND: Chikungunya virus (CHIKV) is a re-emerging arthropod-borne (arbo)virus that causes chikungunya fever in humans and is predominantly transmitted by Aedes aegypti mosquitoes. The CHIKV replication machinery consists of four non-structural proteins (nsP1-4) that additionally require the pre...

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Detalles Bibliográficos
Autores principales: Göertz, Giel P., Lingemann, Marit, Geertsema, Corinne, Abma-Henkens, Marleen H. C., Vogels, Chantal B. F., Koenraadt, Constantianus J. M., van Oers, Monique M., Pijlman, Gorben P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6249005/
https://www.ncbi.nlm.nih.gov/pubmed/30412583
http://dx.doi.org/10.1371/journal.pntd.0006958