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The RNA interactome of human telomerase RNA reveals a coding-independent role for a histone mRNA in telomere homeostasis

Telomerase RNA (TR) provides the template for DNA repeat synthesis at telomeres and is essential for genome stability in continuously dividing cells. We mapped the RNA interactome of human TR (hTR) and identified a set of non-coding and coding hTR-interacting RNAs, including the histone 1C mRNA (HIS...

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Detalles Bibliográficos
Autores principales: Ivanyi-Nagy, Roland, Ahmed, Syed Moiz, Peter, Sabrina, Ramani, Priya Dharshana, Ong, Peh Fern, Dreesen, Oliver, Dröge, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6249008/
https://www.ncbi.nlm.nih.gov/pubmed/30355447
http://dx.doi.org/10.7554/eLife.40037