Analysis of 7,815 cancer exomes reveals associations between mutational processes and somatic driver mutations

Driver mutations are the genetic variants responsible for oncogenesis, but how specific somatic mutational events arise in cells remains poorly understood. Mutational signatures derive from the frequency of mutated trinucleotides in a given cancer sample, and they provide an avenue for investigating...

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Detalles Bibliográficos
Autores principales: Poulos, Rebecca C., Wong, Yuen T., Ryan, Regina, Pang, Herbert, Wong, Jason W. H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6249022/
https://www.ncbi.nlm.nih.gov/pubmed/30412573
http://dx.doi.org/10.1371/journal.pgen.1007779

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6249022/
https://www.ncbi.nlm.nih.gov/pubmed/30412573
http://dx.doi.org/10.1371/journal.pgen.1007779

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