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Generation of uniform-sized multicellular tumor spheroids using hydrogel microwells for advanced drug screening

Even though in vitro co-culture tumor spheroid model plays an important role in screening drug candidates, its wide applications are currently limited due to the lack of reliable and high throughput methods for generating well-defined and 3D complex co-culture structures. Herein, we report the devel...

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Detalles Bibliográficos
Autores principales: Lee, Jong Min, Park, Da Yeon, Yang, Letao, Kim, Eun-Joong, Ahrberg, Christian D., Lee, Ki-Bum, Chung, Bong Geun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6249215/
https://www.ncbi.nlm.nih.gov/pubmed/30464248
http://dx.doi.org/10.1038/s41598-018-35216-7