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Generation of uniform-sized multicellular tumor spheroids using hydrogel microwells for advanced drug screening
Even though in vitro co-culture tumor spheroid model plays an important role in screening drug candidates, its wide applications are currently limited due to the lack of reliable and high throughput methods for generating well-defined and 3D complex co-culture structures. Herein, we report the devel...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6249215/ https://www.ncbi.nlm.nih.gov/pubmed/30464248 http://dx.doi.org/10.1038/s41598-018-35216-7 |