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Melatonin protects endothelial progenitor cells against AGE-induced apoptosis via autophagy flux stimulation and promotes wound healing in diabetic mice

Wound healing is delayed in diabetic patients. Increased apoptosis and endothelial progenitor cell (EPC) dysfunction are implicated in delayed diabetic wound healing. Melatonin, a major secretory product of the pineal gland, promotes diabetic wound healing; however, its mechanism of action remains u...

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Detalles Bibliográficos
Autores principales: Jin, Haiming, Zhang, Zengjie, Wang, Chengui, Tang, Qian, Wang, Jianle, Bai, Xueqin, Wang, Qingqing, Nisar, Majid, Tian, Naifeng, Wang, Quan, Mao, Cong, Zhang, Xiaolei, Wang, Xiangyang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6249246/
https://www.ncbi.nlm.nih.gov/pubmed/30459300
http://dx.doi.org/10.1038/s12276-018-0177-z