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COMP and TSP-4 interact specifically with the novel GXKGHR motif only found in fibrillar collagens
COMP (cartilage oligomeric matrix protein) is a member of the thrombospondin family and forms homopentamers as well as mixed heterooligomers with its closely related family member TSP-4. COMP is long known to bind to collagens and to influence collagen fibril formation. Recent work indicates that al...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6249252/ https://www.ncbi.nlm.nih.gov/pubmed/30464261 http://dx.doi.org/10.1038/s41598-018-35447-8 |