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Glucocorticoids affect bone mineral density and bone remodelling in OVX sheep: A pilot study

The aim of this study was to validate the combination of ovariectomy and glucocorticoid treatment in sheep as a large animal model for osteoporosis by measuring the concentration of specific biomarkers in the blood of the sheep and measuring bone loss over five months. Aged Merino ewes were randomly...

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Detalles Bibliográficos
Autores principales: Cabrera, Diana, Wolber, Frances M., Dittmer, Keren, Rogers, Chris, Ridler, Anne, Aberdein, Danielle, Parkinson, Tim, Chambers, Paul, Fraser, Karl, Roy, Nicole C., Kruger, Marlena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6249392/
https://www.ncbi.nlm.nih.gov/pubmed/30480061
http://dx.doi.org/10.1016/j.bonr.2018.11.001