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Glucocorticoids affect bone mineral density and bone remodelling in OVX sheep: A pilot study
The aim of this study was to validate the combination of ovariectomy and glucocorticoid treatment in sheep as a large animal model for osteoporosis by measuring the concentration of specific biomarkers in the blood of the sheep and measuring bone loss over five months. Aged Merino ewes were randomly...
Autores principales: | Cabrera, Diana, Wolber, Frances M., Dittmer, Keren, Rogers, Chris, Ridler, Anne, Aberdein, Danielle, Parkinson, Tim, Chambers, Paul, Fraser, Karl, Roy, Nicole C., Kruger, Marlena |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6249392/ https://www.ncbi.nlm.nih.gov/pubmed/30480061 http://dx.doi.org/10.1016/j.bonr.2018.11.001 |
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