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Within-host Mycobacterium tuberculosis diversity and its utility for inferences of transmission

Whole genome sequencing in conjunction with traditional epidemiology has been used to reconstruct transmission networks of Mycobacterium tuberculosis during outbreaks. Given its low mutation rate, genetic diversity within M. tuberculosis outbreaks can be extremely limited – making it difficult to de...

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Detalles Bibliográficos
Autores principales: Martin, Michael A., Lee, Robyn S., Cowley, Lauren A., Gardy, Jennifer L., Hanage, William P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Microbiology Society 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6249434/
https://www.ncbi.nlm.nih.gov/pubmed/30303479
http://dx.doi.org/10.1099/mgen.0.000217