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Within-host Mycobacterium tuberculosis diversity and its utility for inferences of transmission
Whole genome sequencing in conjunction with traditional epidemiology has been used to reconstruct transmission networks of Mycobacterium tuberculosis during outbreaks. Given its low mutation rate, genetic diversity within M. tuberculosis outbreaks can be extremely limited – making it difficult to de...
Autores principales: | Martin, Michael A., Lee, Robyn S., Cowley, Lauren A., Gardy, Jennifer L., Hanage, William P. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Microbiology Society
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6249434/ https://www.ncbi.nlm.nih.gov/pubmed/30303479 http://dx.doi.org/10.1099/mgen.0.000217 |
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