Cargando…

In Vitro Effect of the Histone Deacetylase Inhibitor Valproic Acid on Viability and Apoptosis of the PLC/PRF5 Human Hepatocellular Carcinoma Cell Line

The nucleosome is the fundamental building block of eukaryotic chromatin formed by DNA and histone proteins. Chromatin modifications such as acetylation, methylation, and phosphorylation are necessary for protection, replication, and gene transcription. Histone deacetylases (HDACs) are a group of en...

Descripción completa

Detalles Bibliográficos
Autores principales: Sanaei, Masumeh, Kavoosi, Fraidoon, Roustazadeh, Abazar, Shahsavani, Hossein
Formato: Online Artículo Texto
Lenguaje:English
Publicado: West Asia Organization for Cancer Prevention 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6249479/
https://www.ncbi.nlm.nih.gov/pubmed/30256044
http://dx.doi.org/10.22034/APJCP.2018.19.9.2507