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Carbonic anhydrase 12 mutation modulates membrane stability and volume regulation of aquaporin 5

Patients carrying the carbonic anhydrase12 E143K mutation showed the dry mouth phenotype. The mechanism underlying the modulation of aquaporin 5 and function in the salivary glands by carbonic anhydrase12 remains unknown. In this study, we identified the mislocalised aquaporin 5 in the salivary glan...

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Detalles Bibliográficos
Autores principales: Hwang, Soyoung, Kang, Jung Yun, Kim, Min Jae, Shin, Dong Min, Hong, Jeong Hee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6249555/
https://www.ncbi.nlm.nih.gov/pubmed/30451023
http://dx.doi.org/10.1080/14756366.2018.1540475