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Postexposure Efficacy of Recombinant Vesicular Stomatitis Virus Vectors Against High and Low Doses of Marburg Virus Variant Angola in Nonhuman Primates

A recombinant vesicular stomatitis virus (rVSV) expressing the Marburg virus (MARV) Musoke variant glycoprotein fully protects macaques against 2 MARV variants and Ravn virus as a preventive vaccine and MARV variant Musoke as a postexposure treatment. To evaluate postexposure efficacy against the mo...

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Detalles Bibliográficos
Autores principales: Woolsey, Courtney, Geisbert, Joan B, Matassov, Demetrius, Agans, Krystle N, Borisevich, Viktoriya, Cross, Robert W, Deer, Daniel J, Fenton, Karla A, Eldridge, John H, Mire, Chad E, Geisbert, Thomas W
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6249565/
https://www.ncbi.nlm.nih.gov/pubmed/29939296
http://dx.doi.org/10.1093/infdis/jiy293