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Fully Human Immunoglobulin G From Transchromosomic Bovines Treats Nonhuman Primates Infected With Ebola Virus Makona Isolate

Transchromosomic bovines (Tc-bovines) adaptively produce fully human polyclonal immunoglobulin (Ig)G antibodies after exposure to immunogenic antigen(s). The National Interagency Confederation for Biological Research and collaborators rapidly produced and then evaluated anti-Ebola virus IgG immunogl...

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Detalles Bibliográficos
Autores principales: Luke, Thomas, Bennett, Richard S, Gerhardt, Dawn M, Burdette, Tracey, Postnikova, Elena, Mazur, Steven, Honko, Anna N, Oberlander, Nicholas, Byrum, Russell, Ragland, Dan, St. Claire, Marisa, Janosko, Krisztina B, Smith, Gale, Glenn, Gregory, Hooper, Jay, Dye, John, Pal, Subhamoy, Bishop-Lilly, Kimberly A, Hamilton, Theron, Frey, Kenneth, Bollinger, Laura, Wada, Jiro, Wu, Hua, Jiao, Jin-an, Olinger, Gene G, Gunn, Bronwyn, Alter, Galit, Khurana, Surender, Hensley, Lisa E, Sullivan, Eddie, Jahrling, Peter B
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6249570/
https://www.ncbi.nlm.nih.gov/pubmed/30010950
http://dx.doi.org/10.1093/infdis/jiy377