Solutol HS15 based binary mixed micelles with penetration enhancers for augmented corneal delivery of sertaconazole nitrate: optimization, in vitro, ex vivo and in vivo characterization

Keratomycosis is a serious corneal disease that can cause a permanent visual disability if not treated effectively. Sertaconazole nitrate (STZ), a novel broad spectrum antifungal drug, was suggested as a promising treatment. However, its utility in the ocular route is restricted by its poor solubili...

Descripción completa

Detalles Bibliográficos
Autores principales: Younes, Nihal Farid, Abdel-Halim, Sally Adel, Elassasy, Abdelhalim I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6249589/
https://www.ncbi.nlm.nih.gov/pubmed/30442039
http://dx.doi.org/10.1080/10717544.2018.1497107

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6249589/
https://www.ncbi.nlm.nih.gov/pubmed/30442039
http://dx.doi.org/10.1080/10717544.2018.1497107

Ejemplares similares