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Influences of donor and host age on human muscle-derived stem cell-mediated bone regeneration

BACKGROUND: Human muscle-derived stem cells (hMDSCs) have been shown to regenerate bone efficiently when they were transduced with Lenti-viral bone morphogenetic protein 2 (LBMP2). However, whether the age of hMDSCs and the animal host affect the bone regeneration capacity of hMDSCs and mechanism ar...

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Detalles Bibliográficos
Autores principales: Gao, Xueqin, Lu, Aiping, Tang, Ying, Schneppendahl, Johannes, Liebowitz, Andrea B., Scibetta, Alex C., Morris, Elizabeth R., Cheng, Haizi, Huard, Charles, Amra, Sarah, Wang, Bing, Hall, Mary A., Lowe, Walter R., Huard, Johnny
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6249775/
https://www.ncbi.nlm.nih.gov/pubmed/30463597
http://dx.doi.org/10.1186/s13287-018-1066-z