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Replacing nonmuscle myosin 2A with myosin 2C1 permits gastrulation but not placenta vascular development in mice

Three paralogues of nonmuscle myosin 2 (NM 2A, 2B, and 2C) are expressed in mammals, and the heavy chains are the products of three different genes (Myh9, Myh10, and Myh14, respectively). NM 2A and 2B are essential for mouse development, while 2C is not. Studies on NM 2C are limited and the in vivo...

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Detalles Bibliográficos
Autores principales: Zhang, Yingfan, Liu, Chengyu, Adelstein, Robert S., Ma, Xuefei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6249808/
https://www.ncbi.nlm.nih.gov/pubmed/30044719
http://dx.doi.org/10.1091/mbc.E17-12-0713