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Digestion of the glycosaminoglycan extracellular matrix by chondroitinase ABC supports retinal ganglion cell dendritic preservation in a rodent model of experimental glaucoma

Retinal ganglion cell dendritic atrophy is an early feature of glaucoma, and the recovery of retinal ganglion cell dendrites is a viable option for vision improvement in glaucoma. Retinal ganglion cell neurites are surrounded by a specialised glycosaminoglycan extracellular matrix which inhibits den...

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Detalles Bibliográficos
Autores principales: Tribble, James R., Williams, Pete A., Caterson, Bruce, Sengpiel, Frank, Morgan, James E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6249825/
https://www.ncbi.nlm.nih.gov/pubmed/30463575
http://dx.doi.org/10.1186/s13041-018-0412-5